ISSN : 2146-3123
E-ISSN : 2146-3131

Prevalence of Multiple Sclerosis in the Metropolitan Area of Edirne City, Turkey
Yahya Çelik 1, Özlem Birgili 2, Hakan Yılmaz 2, Aslı Kiyat 3, Sebahattin Saip 3, Aksel Siva 3, Baburhan Güldiken 4, Hülya Özkan 5, Dilek Kuşçu 6, Nevin Sütlas 6, Jale Ağaoğlu 7, Ufuk Utku 8
1Departments of Neurology, Medical Faculty of Trakya University, Edirne
2Department of Neurology, Edirne State Hospital, Edirne, Turkey
3Cerrahpaşa Medical Faculty, Department of Neurology, İstanbul University, İstanbul, Turkey
4Department of Neurology, School of Medicine, Trakya University, Edirne, Turkey
5Edirne Devlet Hastanesi Nöroloji Kliniği, Edirne
6Department of Neurology, Bakırköy State Hospital, İstanbul, Turkey
7Department of Neurology, Okmeyadanı State Hospital, İstanbul, Turkey
8Trakya Üniversitesi Tıp Fakültesi Nöroloji Anabilim Dalı, Edirne
DOI : 10.5174/tutfd.2010.04089.0
Pages : 193-196


Objective: The prevalence and incidence of multiple sclerosis may vary according to the influence of the altitude of a geographical area as well as the genetic and environmental factors. This study ained to determine the incidence and prevalence of multiple sclerosis in Edirne population.

Material and Methods: Patients with a definite diagnosis of MS according to McDonald's criteria, admitted to one of the three MS clinics in Edirne, were included in this two-stage study. Also the records of hospitals in İstanbul serving patients from Edirne, have been evaluated.

Results: The prevalence rate of confirmed MS patients was 33.9/100000 (95% CI: 32-36) in 2003. The mean annual incidence was 3.48/100000 (95% CI: 2.90-4.00). Mean age of the patients was 36.5±9.6 years. Mean age at onset was 29.2±8.5 years. Mean duration of disease was 6.9±5.2 years. Overall, 69.2% had a relapsing-remitting course, 20.5% had a primary progressive course and 10.3% had a secondary progressive course. Mean Expanded Disability Status Scale score was 3.04±2.18. The prevalence and annual incidence after one year was 36.5 per 100000 (95% CI: 33.2-38.6) and 2.60 per 100000 (95% CI: 2.1-3.8), respectively.

Conclusion: This is the first city-based MS prevalence study performed in Turkey. The MS prevalence in Edirne is similar to that of Greece and Bulgaria but lower than that of European countries.

Keywords : Multiple Sclerosis, prevalance, incidence, epidemiology, Turkey

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